2024
243

Discovering Fragile Clades And Causal Sequences In Phylogenomics By Evolutionary Sparse Learning

Molecular Biology and Evolution | 41:msae131 (13 pp)

S. Sharma, S. Kumar

242

Methods for Estimating Personal Disease Risk and Phylogenetic Diversity of Hematopoietic Stem Cells

Molecular Biology and Evolution | 41:msad279 (11 pp)

J.M. Craig, G.S. Gerhard, S. Sharma, A. Yankovskiy, S. Miura, S. Kumar

241

Visualizing Genomic Medicine: An Introduction to General Biology

The American Biology Teacher | 86:265–273 (9 pp)

C. Babaian, S. Kumar

240

Of Phylogenies and Tumors: Cancer as a Model System to Teach Evolution

The American Biology Teacher | 86:62–70 (9 pp)

C. Babaian, S. Kumar

239

Some Mechanistic Underpinnings of Molecular Adaptations of SARS-COV-2 Spike Protein by Integrating Candidate Adaptive Polymorphisms with Protein Dynamics

eLife | 12:RP92063 (25 pp)

N. Ose, P. Campitelli, T. Modi, I. Kazan, S. Kumar, B. Ozkan

238

Analyses of Allele Age and Fitness Impact Reveal Human Beneficial Alleles to be Older than Neutral Controls

eLife | 13:RP93258 (27 pp)

A. Pivirotto, A. Platt, R. Patel, S. Kumar, J. Hey

237

Completing a Molecular Timetree of Primates

Frontiers in Bioinformatics | 4:(accepted)

J.M. Craig, S.B. Hedges, S. Kumar

236

MEGA12: Molecular Evolutionary Genetics Analysis version 12 for adaptive and green computing

Molecular Biology and Evolution | (in review)

S. Kumar, G. Stecher, M. Suleski, M. Sanderford, S. Sharma, K. Tamura

235

MyESL: Sparse learning in molecular evolution and phylogenetic analysis

Bioinformatics | (in review)

M. Sanderford, S. Sharma, G. Stecher, J. Liu, J. Ye, S. Kumar

234

STICI: Split-Transformer with Integrated Convolutions for Imputation

Nature Communications | (in revision)

M.E. Mowlaei, C. Li, O. Jamialahmadi, R. Dias, J. Chen, B. Jamialahmadi, T.R. Rebbeck, V. Carnevale, S. Kumar, X. Shi

233

Evolutionary Sparse Learning Reveals the Shared Genetic Basis of Convergent Traits

bioRxiv | (in revision)

J. Allard , S. Sharma , R. Patel , M. Sanderford , K. Tamura , S. Vucetic , G. Gerhard, S. Kumar

232

Integrating Phylogenies with Chronology to Assemble the Tree of Life

Bioinformatics | (in revision)

J. Barba-Montoya, J.M. Craig, S. Kumar

231

R3F: An R Package for Evolutionary Dates, Rates, and Priors using Relative Rate Framework

bioRxiv | (available)

Q. Tao, S. Sharma, K. Tamura, S. Kumar

2023
230

Computational Reproducibility of Molecular Phylogenies

Molecular Biology and Evolution | 40:msad165 (9 pp)

S. Kumar, Q. Tao, A. P. Lamarca, K. Tamura

229

Completing a Molecular Timetree of Apes and Monkeys

Frontiers in Bioinformatics | 3:1284744 (8 pp)

J.M. Craig, G. Bamba, J. Barba-Montoya, S.B. Hedges, S. Kumar

228

Molecular Timetrees using Relaxed Clocks and Uncertain Phylogenies

Frontiers in Bioinformatics | 3:1225807 (13 pp)

J. Barba-Montoya, S. Sharma, S. Kumar

227

The Origin of Eukaryotes and Rise in Complexity were Synchronous with the Rise in Oxygen

Frontiers in Bioinformatics | 3:1233281 (10 pp)

J. M. Craig, S. Kumar, S. B. Hedges

226

Discovering Research Articles Containing Evolutionary Timetrees by Machine Learning

Bioinformatics | 39:btad035 (7 pp)

M. Stanojevic, J. Andjelkovic, A. Kasprowicz, L.A. Huuki, J. Chao, S.B. Hedges, S. Kumar, Z. Obradovic

225

Improving Cellular Phylogenies through the Integrated Use of Mutation Order and Optimality Principles

Computational and Structural Biotechnology Journal | 21:3894–3903

S. Miura, T. Dolker, M. Sanderford, S. Kumar

224

Bootstrap Confidence for Molecular Evolutionary Estimates from Tumor Bulk Sequencing Data

Frontiers in Bioinformatics | 3:1090730 (11 pp)

J. Huzar, M. Shenoy, M. D. Sanderford, S. Kumar, S. Miura

223

Protein Dynamics Provide Mechanistic Insights about Epistasis among Common Missense Polymorphisms

Biophysical Journal | 122:2938–2947

N. J. Ose, P. Campitelli, R. Patel, S. Kumar, S. B. Ozkan

222

Gene Expression Study of Breast Cancer using Welch Satterthwaite t-test, Kaplan-Meier Estimator Plot and Huber Loss Robust Regression Model

Journal of King Saud University - Science | 35:102447 (9 pp)

S. Karim, M.S. Iqbal, N. Ahmad, M.S. Ansari, Z. Mirza, A. Merdad, S. Jastaniah, S. Kumar

221

Masatoshi Nei (1931–2023)

Nature Ecology & Evolution | 7:(2 pp)

J. Zhang, S. Kumar

220

Masatoshi Nei (1931–2023)

Molecular Biology and Evolution | 40:msad149 (5 pp)

S. Kumar, T. Gojobori

2022
219

Embracing Green Computing in Molecular Phylogenetics

Molecular Biology and Evolution | 39:msac043 (4 pp)

S. Kumar

218

TimeTree 5: An Expanded Resource for Species Divergence Times

Molecular Biology and Evolution | 39:msac174 (6 pp)

S. Kumar, M. Suleski, J. M. Craig, A. E. Kasprowicz, M. Sanderford, M. Li, G. Stecher, S. B. Hedges

217

Taming the Selection of Optimal Substitution Models in Phylogenomics by Site Subsampling and Upsampling

Molecular Biology and Evolution | 39:msac236 (8 pp)

S. Sharma, S. Kumar

216

TopHap: Rapid Inference of Key Phylogenetic Structures from Common Haplotypes in Large Genome Collections with Limited Diversity

Bioinformatics | 38:2719–2726

M. Caraballo-Ortiz, S. Miura, M. Sanderford, T. Dolker, Q. Tao, S. Weaver, S. L. K. Pond, S. Kumar

215

Epistasis Creates Invariant Sites and Modulates the Rate of Molecular Evolution

Molecular Biology and Evolution | 39:msac106 (11 pp)

R. Patel, V. Carnevale, S. Kumar

214

Dynamic Coupling of Residues within Proteins as a Mechanistic Foundation of Many Enigmatic Pathogenic Missense Variants

PLoS Computational Biology | 18:e1010006 (22 pp)

N. J. Ose, B. M. Butler, A. Kumar, M. Sanderford, S. Kumar, S. B. Ozkan

213

Limitations of Phylogenomic Data Can Drive Inferred Speciation Rate Shifts

Molecular Biology and Evolution | 39:msac038 (11 pp)

J. M. Craig, S. Kumar, S. B. Hedges

212

Storyboarding for Biology: An Authentic STEAM Experience

The American Biology Teacher | 84:328–335

C. Babaian, S. Kumar

211

Epistasis Storyboarded

The American Biology Teacher | 84:562–569

C. Babaian, S. Kumar

210

Clone Phylogenetics Reveals Metastatic Tumor Migrations, Maps, and Models

Cancers | 14:4326 (13 pp)

A. Chroni, S. Miura, L. Hamilton, T. Vu, S.G. Gaffney, V. Aly, S. Karim, M. Sanderford, J.P. Townsend, S. Kumar

209

A Phylogenetic Approach to Study the Evolution of Somatic Mutational Processes in Cancer

Communications Biology | 5:617 (11 pp)

S. Miura, T. Vu, J. Choi, J. P. Townsend, S. Karim, S. Kumar

208

MOCA for Integrated Analysis of Gene Expression and Genetic Variation in Single Cells

Frontiers in Genetics | 13:831040 (8 pp)

J. Huzar, H. Kim, S. Kumar, S. Miura

207

Waiting for the Truth: Is Reluctance in Accepting an Early Origin Hypothesis for SARS-CoV-2 Delaying Our Understanding of Viral Emergence?

BMJ Global Health | 7:e008386 (8 pp)

M. Canuti, S. Bianchi, O. Kolbl, S.L.K. Pond, S. Kumar, M. Gori, C. Fappani, D. Colzani, E. Borghi, G.V. Zuccotti, M.C. Raviglione, E. Tanzi, A. Amendola

206

Molecular Evidence for SARS-CoV-2 in Samples Collected from Patients with Morbilliform Eruptions since Late Summer 2019 in Lombardy, Northern Italy

Environmental Research | 215:113979 (9 pp)

A. Amendola, M. Canuti, S. Bianchi, S. Kumar, C. Fappani, M. Gori, D. Colzani, S. L. K. Pond, S. Miura, M. Baggeri, A. Marchi, E. Borghi, G. V. Zuccotti, M. C. Raviglione, F. Magurano, E. Tanzi

205

Development of "Biosearch System" for Biobank Management and Storage of Disease Associated Genetic Information

Journal of King Saud University - Science | 34:101760 (10 pp)

S. Karim, M. Al-Kharraz, Z. Mirza, H. Noureldin, H. Abusamara, N. Alganmi, A. Merdad, S. Jastaniah, S. Kumar, M. Rasool, A. Abuzenadah, M. Al-Qahtani

2021
203

Evolutionary Sparse Learning for Phylogenomics

Molecular Biology and Evolution | 38:4674–4682

S. Kumar, S. Sharma

202

Fast and Accurate Bootstrap Confidence Limits on Genome-scale Phylogenies using Little Bootstraps

Nature Computational Science | 1:573–577

S. Sharma, S. Kumar

201

Tumors are Evolutionary Island-like Ecosystems

Genome Biology and Evolution | 13:evab276 (11 pp)

A. Chroni, S. Kumar

200

Migrations of Cancer Cells through the Lens of Phylogenetic Biogeography

Scientific Reports | 11:17184 (13 pp)

A. Chroni, S. Miura, O. Oladeinde, V. Aly, S. Kumar

199

Data-driven Speciation Tree Prior for Better Species Divergence Times in Calibration-poor Molecular Phylogenies

Bioinformatics | 37:i102–i110

Q. Tao, J. Barba-Montoya, S. Kumar

198

Epistasis Produces an Excess of Invariant Sites in Neutral Molecular Evolution

Proceedings of the National Academy of Sciences (USA) | 118:e2018767118

R. Patel and S. Kumar

197

MEGA11: Molecular Evolutionary Genetics Analysis Version 11

Molecular Biology and Evolution | 38:3022–3027

K. Tamura, G. Stecher, S. Kumar

196

Molecular Dating for Phylogenies Containing a Mix of Populations and Species by Using Bayesian and RelTime Approaches

Molecular Ecology Resources | 21:122–136

B. Mello, Q. Tao, J. Barba-Montoya, S. Kumar

195

How to Build a Super Predator: From Genotype to Phenotype

The American Biology Teacher | 83:138–146

C. Babaian, S. Kumar

194

Assessing Rapid Relaxed-Clock Methods for Phylogenomic Dating

Genome Biology and Evolution | 13:evab251 (14 pp)

J. Barba-Montoya, Q. Tao, S. Kumar

193

Molecular and Morphological Clocks for Estimating Evolutionary Divergence Times

BMC Ecology and Evolution | 21:83 (15 pp)

J. Barba-Montoya, Q. Tao, S. Kumar

192

Deep Low-Shot Learning for Biological Image Classification and Visualization from Limited Training Samples

IEEE Transactions on Neural Networks and Learning Systems | (11 pp)

L. Cai, Z. Wang, R. Kulathinal, S. Kumar, S. Ji

191

Common Treatment, Common Variant: Evolutionary Prediction of Functional Pharmacogenomic Variants

Journal of Personalized Medicine | 11:131 (13 pp)

L. B. Scheinfeldt, A. Brangan, D. Kusic, S. Kumar, N. Gharani

190

TreeMap: A Structured Approach to Fine Mapping of eQTL Variants

Bioinformatics | 37:1125–1134

L. Liu, P. Chandrashekar, B. Zeng, M. D. Sanderford, S. Kumar, G. Gibson

189

The Durability of Immunity against Reinfection by SARS-CoV-2: A Comparative Evolutionary Study

The Lancet Microbe | 12:e666–e675

J. P. Townsend, H. B. Hassler, Z. Wang, S. Miura, J. Singh, S. Kumar, N. Ruddle, A.P. Galvani, A. Dornburg

188

The Somatic Molecular Evolution of Cancer: Mutation, Selection, and Epistasis

Progress in Biophysics and Molecular Biology | 165:56–65

K. Dasari, J. A. Somarelli, S. Kumar, J. P. Townsend

2020
187

PathFinder: Bayesian Inference of Clone Migration Histories in Cancer

Bioinformatics | 36:i675–i683

S. Kumar, A. Chroni, K. Tamura, M. Sanderford, O. Oladeinde, V. Aly, T. Vu, S. Miura

186

Efficient Methods for Dating Evolutionary Divergences

in The Molecular Evolutionary Clock (ed. Ho) [Springer] | 197–219

Q. Tao, K. Tamura, S. Kumar

185

Where Did SARS-CoV-2 Come From?

Molecular Biology and Evolution | 37:2463–2464

T. Leitner, S. Kumar

184

Molecular Evolutionary Genetics Analysis (MEGA) for macOS

Molecular Biology and Evolution | 37:1237–1239

G. Stecher, K. Tamura, S. Kumar

183

A New Method for Inferring Timetrees from Temporally Sampled Molecular Sequences

PLoS Computational Biology | 16:e1007046 (24 pp)

S. Miura, K. Tamura, Q. Tao, L. A. Huuki, S. L. K. Pond, J. Priest, J. Deng, S. Kumar

182

Reliable Confidence Intervals for RelTime Estimates of Evolutionary Divergence Times

Molecular Biology and Evolution | 37:280–290

Q. Tao, K. Tamura, B. Mello, S. Kumar

181

Power and Pitfalls of Computational Methods for Inferring Clone Phylogenies and Mutation Orders from Bulk Sequencing Data

Scientific Reports | 10:3498 (21 pp)

S. Miura, T. Vu, J. Deng, T. Buturla, J. Choi, S. Kumar

180

Relative Efficiencies of Simple and Complex Substitution Models in Estimating Divergence Times in Phylogenomics

Molecular Biology and Evolution | 37:1819–1831

Q. Tao, J. Barba-Montoya, L. A. Huuki, M. K. Durnan, S. Kumar

179

Using a GTR+Gamma Substitution Model for Dating Sequence Divergence when Stationarity and Time-reversibility Assumptions are Violated

Bioinformatics | 36:i884–i894

J. Barba-Montoya, Q. Tao, S. Kumar

178

The Bits and Bytes of Biology: Digitalization Fuels an Emerging Generative Platform for Biological Innovation

Handbook of Digital Innovation (ed. Nambisan, Lyytinen, Yoo) [Edward Elgar] | 253–265

R. J. Kulathinal, Y. Yoo, S. Kumar

177

Molecular Memories of a Cambrian Fossil

The American Biology Teacher | 82:586–595

C. Babaian, S. Kumar

176

Functional, Morphological, and Evolutionary Characterization of Hearing in Subterranean, Eusocial African Mole-Rats

Current Biology | 30:(18 pp)

S. J. Pyott, M. van Tuinen, L. A. Screven, K. M. Schrode, J. Bai, C. M. Barone, S. D. Price, A. Lysakowski, M. Sanderford, S. Kumar, J. Santos-Sacchi, A. M. Lauer, T. J. Park

175

Interactive Effect of TLR SNPs and Exposure to Sexually Transmitted Infections on Prostate Cancer Risk in Jamaican Men

The Prostate | 80:4329–4341.e4

B. Dubey, M. Jackson, C. Zeigler-Johnson, K. Devarajan, R. E. Flores-Obando, N. McFarlane-Anderson, M. Tulloch-Reid, W. Aiken, K. Kimbro, D. Reed, L. R. Kidd, D. Gibbs, S. Kumar, C. Ragin

174

Beaver and Naked Mole Rat Genomes Reveal Common Paths to Longevity

Cell Reports | 32:(13 pp)

X. Zhou, Q. Dou, G. Fan, Q. Zhang, M. Sanderford, A. Kaya, J. Johnson, E. Karlsson, X. Tian, A. Mikhalchenko, S. Kumar, A. Seluanov, Z. Zhang, V. Gorbunova, X. Liu, and V. N. Gladyshev

173

Somatic Selection Distinguishes Oncogenes and Tumor Suppressor Genes

Bioinformatics | 36:1712–1717

P. Chandrashekar, N. Ahmadinejad, J. Wang, A. Sekulic, J. B. Egan, Y. W. Asmann, S. Kumar, C. Maley, L. Liu

172

The Role of Conformational Dynamics and Allostery in Modulating Protein Evolution

Annual Review of Biophysics | 49:267–288

P. Campitelli, T. Modi, S. Kumar, S. B. Ozkan

171

Molecular Biology and Evolution of Cancer: From Discovery to Action

Molecular Biology and Evolution | 37:320–326

J. A. Somarelli, H. Gardner, V. L. Cannataro, E. F. Gunady, A. M. Boddy, N. A. Johnson, J. N. Fisk, S. G. Gaffney, J. H. Chuang, S. Li, F. D. Ciccarelli, A. R. Panchenko, K. Megquier, S. Kumar, A. Dornburg, J. DeGregori, J. P. Townsend

170

Deep Model Based Transfer and Multi-task Learning for Biological Image Analysis

IEEE Transactions on Big Data | 6:322–333

W. Zhang, R. Li, T. Zeng, Q. Sun, S. Kumar, J. Ye, S. Ji

2019
169

Biological Relevance of Computationally Predicted Pathogenicity of Noncoding Variants

Nature Communications | 10:330 (11 pp)

L. Liu, M. D. Sanderford, R. Patel, P. B. Chandrashekar, G. Gibson, S. Kumar

168

Delineation of Tumor Migration Paths by Using a Bayesian Biogeographic Approach

Cancers | 11:12 (14 pp)

A. Chroni, T. Vu, S. Miura, S. Kumar

167

Adventures in Evolution: The Narrative of Tardigrada, Trundlers in Time

The American Biology Teacher | 81:543–552

C. Babaian, S. Kumar

166

On Estimating Evolutionary Probabilities of Population Variants

BMC Evolutionary Biology | 19:133 (14 pp)

R. Patel, S. Kumar

165

A Machine Learning Method for Detecting Autocorrelation of Evolutionary Rates in Large Phylogenies

Molecular Biology and Evolution | 36:811–824

Q. Tao, K. Tamura, F. Battistuzzi, S. Kumar

164

Genome-wide Analysis Indicates Association between Heterozygote Advantage and Healthy Aging in Humans

BMC Genetics | 20:52 (14 pp)

K. Xu, R. Kosoy, K. Shameer, S. Kumar, L. Liu, B. Readhead, G. M. Belbin, H. C. Lee, R. Chen, J. T. Dudley

2018
163

MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms

Molecular Biology and Evolution | 35:1547–1549

S. Kumar, G. Stecher, M. Li, C. Knyaz, K. Tamura

162

Theoretical Foundation of the RelTime Method for Estimating Divergence Times from Variable Evolutionary Rates

Molecular Biology and Evolution | 35:1770–1782

K. Tamura, Q. Tao, S. Kumar

161

Accurate Timetrees Require Accurate Calibrations

Proceedings of the National Academy of Sciences (USA) | 115:E9510–E9511

S. B. Hedges, Q. Tao, M. Walker, S. Kumar

160

Neutral Theory, Disease Mutations, and Personal Exomes

Molecular Biology and Evolution | 35:1297–1303

S. Kumar, R. Patel

159

Somatic Evolutionary Timings of Driver Mutations

BMC Cancer | 18:85 (10 pp)

K. Gomez, S. Miura, L. A. Huuki, B.S. Spell, J.P. Townsend, S. Kumar

158

RelTime Relaxes the Strict Molecular Clock throughout the Phylogeny

Genome Biology and Evolution | 10:1631–1636

F. U. Battistuzzi, Q. Tao, L. Jones, K. Tamura, S. Kumar

157

Adaptive Landscape of Protein Variation in Human Exomes

Molecular Biology and Evolution | 35:2015–2025

R. Patel, L. B. Scheinfeldt, M. D. Sanderford, T. R. Lanham, K. Tamura, A. Platt, B. S. Gilksberg, K. Xu, J. T. Dudley, S. Kumar

156

Predicting Clone Genotypes from Tumor Bulk Sequencing of Multiple Samples

Bioinformatics | 34:4017–4026

S. Miura, K. Gomez, O. Murillo, L. A. Huuki, T. Vu, T. Buturla, S. Kumar

155

Computational Enhancement of Single-cell Sequences for Inferring Tumor Evolution

Bioinformatics | 34:i917–i926

S. Miura, L. A. Huuki, T. Buturla, T. Vu, K. Gomez, S. Kumar

2017
154

FlyExpress 7: An Integrated Discovery Platform to Study Coexpressed Genes Using in situ Hybridization Images in Drosophila

G3: Genes, Genomes, Genetics | 7:2791–2797

S. Kumar, C. Konikoff, M. Sanderford, L. Liu, S. Newfeld, J. Ye, R.J. Kulathinal

153

TimeTree: A Resource for Timelines, Timetrees, and Divergence Times

Molecular Biology and Evolution | 34:1812–1819

S. Kumar, G. Stecher, M. Suleski, S. B. Hedges

152

Fast and Accurate Estimates of Divergence Times from Big Data

Molecular Biology and Evolution | 34:45–50

B. Mello, Q. Tao, K. Tamura, S. Kumar

151

The Reliability and Stability of an Inferred Phylogenetic Tree from Empirical Data

Molecular Biology and Evolution | 34:718–723

Y. Katsura, C. Stanley, S. Kumar, M. Nei

2016
150

e-GRASP: An Integrated Evolutionary and GRASP Resource for Exploring Disease Associations

BMC Genomics | 17:770 (8 pp)

S. Karim, H.F. Nour Eldin, H. Abusamra, N. Salem, E. Alhathli, J. Dudley, M.D. Sanderford, L.B. Scheinfeldt A.G. Chaudhary, M.H. Al-Qahtani, S. Kumar

149

MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets

Molecular Biology and Evolution | 33:1870–1874

S. Kumar, G. Stecher, K. Tamura

148

A Molecular Evolutionary Reference for the Human Variome

Molecular Biology and Evolution | 33:245–254

L. Liu, K. Tamura, M.D. Sanderford, V. Gray, S. Kumar

147

Advances in Time Estimation Methods for Molecular Data

Molecular Biology and Evolution | 33:863–869

S. Kumar, S.B. Hedges

2015
146

Integration of Structural Dynamics and Molecular Evolution via Protein Interaction Networks: A New Era in Genomic Medicine

Current Opinion in Structural Biology | 35:135–142

A. Kumar, B.M Butler, S. Kumar, S.B. Ozkan

145

Using Disease-associated Coding Sequence Variation to Investigate Functional Compensation by Human Paralogous Proteins

Evolutionary Bioinformatics | 11:245–251

S. Miura, S. Tate, S. Kumar

144

A Protocol for Diagnosing the Effect of Calibration Priors on Posterior Time Estimates: A Case Study for the Cambrian Explosion of Animal Phyla

Molecular Biology and Evolution | 32:1907–1912

F.U. Battistuzzi, P. Billing-Ross, O. Murillo, A. Filipski, S. Kumar

143

Conformational Dynamics of Nonsynonymous Variants at Protein Interfaces Reveals Disease Association

Proteins | 83:428–435

B.M. Butler, Z.N. Gerek, S. Kumar, S.B. Ozkan

142

Phylogenetic Placement of Metagenomic Reads Using the Minimum Evolution Principle

BMC Genomics | 16:S13 (9 pp)

A. Filipski, K. Tamura, P. Billing-Ross, O. Murillo, S. Kumar

141

Evolutionary Diagnosis of Non-synonymous Variants Involved in Differential Drug Response

BMC Medical Genomics | 8:S6 (6 pp)

N.Z. Gerek, L. Liu, K. Gerold, P. Biparva, E.D. Thomas, S. Kumar

140

Tree of Life Reveals Clock-like Speciation and Diversification

Molecular Biology and Evolution | 32:835–845

S.B. Hedges, J. Marin, M. Suleski, M. Paymer, S. Kumar

139

Exceptional Reduction of the Plastid Genome of Saguaro Cactus (Carnegiea gigantea): Loss of the Ndh Gene Suite and Inverted Repeat

American Journal of Botany | 102:1115–1127

M. Sanderson, D. Copetti, A. Burquez, E. Bustamante, J.L.M. Charboneau, L.E. Eguiarte, S. Kumar, H.O. Lee, J. Lee, M. McMahon, K. Steele, R. Wing, T.J. Yang, D. Zwickl, M.F. Wojciechowski

2014
138

Prospects for Building Large Timetrees using Molecular Data with Incomplete Gene Coverage among Species

Molecular Biology and Evolution | 31:2542–2550

A. Filipski, O. Murillo, A. Freydenzon, K. Tamura, S. Kumar

137

Signatures of Natural Selection on Mutations of Residues with Multiple Posttranslational Modifications

Molecular Biology and Evolution | 31:1641–1645

V.E. Gray, L. Liu, R. Nirankari, P.V. Hornbeck, S. Kumar

136

No Positive Selection for G Allele in a p53 Response Element in Europeans

Cell | 157:1497–1499

S. Kumar, L. Liu

135

Reply to: "Proper Reporting of Predictor Performance"

Nature Methods | 11:781–782

S. Kumar, J. Ye, L. Liu

134

myFX: A Turn-key Software for Laboratory Desktops to Analyze Spatial Patterns of Gene Expression in Drosophila Embryos

Bioinformatics | 30:1319–1321

I. Montiel, C. Konikoff, B. Braun, M. Packard, S.L. Gramates, Q. Sun, J. Ye, S. Kumar

133

MEGA-MD: Molecular Evolutionary Genetics Analysis Software with Mutational Diagnosis of Amino Acid Variation

Bioinformatics | 30:1305–1307

G. Stecher, L. Liu, M.D. Sanderford, D. Peterson, K. Tamura, S. Kumar

132

Automated Annotation of Developmental Stages of Drosophila Embryos in Images Containing Spatial Patterns of Expression

Bioinformatics | 30:266–273

L. Yuan, C. Pan, S. Ji, M. McCutchan, Z.H. Zhou, S. J. Newfeld, S. Kumar, J. Ye

131

Whole-genome Sequencing of the Snub-nosed Monkey Provides Insights into Folivory and Evolutionary History

Nature Genetics | 46:1303–1310

X. Zhou, B. Wang, Q. Pan, J. Zhang, S. Kumar, X. Sun, Z. Liu, H. Pan, Y. Lin, G. Liu, W. Zhan, M. Li, B. Ren, X. Ma, H. Ruan, C. Cheng, D. Wang, F. Shi, Y. Hui, Y. Tao, C. Zhang, P. Zhu, Z. Xiang, W. Jiang, J. Chang, H. Wang, Z. Cao, Z. Jiang, B. Li, G. Yang, C. Roos, P.A. Garber, M.W. Bruford, R. Li, M. Li

2013
130

The Evolutionary History of Amino Acid Variations Mediating Increased Resistance of S. aureus Identifies Reversion Mutations in Metabolic Regulators

PLoS One | 8:e56466 (9 pp)

M.D. Champion, V. Gray, C. Eberhard, S. Kumar

129

Structural Dynamics Flexibility Informs Function and Evolution at a Proteome Scale

Evolutionary Applications | 6:423–433

Z.N. Gerek, S. Kumar, S.B. Ozkan

128

GRASP [Genomic Resource Access for Stoichioproteomics]: Comparative Explorations of the Atomic Content of 12 Drosophila Proteomes

BMC Genomics | 14:(14 pp)

J.D.J. Gilbert, C. Acquisti, H.M. Martinson, J.J. Elser, S. Kumar, W.F. Fagan

127

Evolutionary Balancing is Critical for Correctly Forecasting Disease-associated Amino Acid Variants

Molecular Biology and Evolution | 30:1252–1257

L. Liu, S. Kumar

126

Image-level and Group-level Models for Drosophila Gene Expression Pattern Annotation

BMC Bioinformatics | 14:350 (13 pp)

Q. Sun, S. Muckatira, L. Yuan, S. Ji, S. Newfeld, S. Kumar, J. Ye

125

MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0

Molecular Biology and Evolution | 30:2725–2729

K. Tamura, G. Stecher, D. Peterson, A. Filipski, S. Kumar

124

Genome-wide Profiling of Human Cap-independent Translation-enhancing Elements

Nature Methods | 10:747–750

B.P. Wellensiek, A.C. Larsen, B. Stephens, K. Kukurba, K. Waern, N. Briones, L. Liu, M. Snyder, B. L. Jacobs, S. Kumar, J.C. Chaput

123

A Mesh Generation and Machine Learning Framework for Drosophila Gene Expression Pattern Image Analysis

BMC Bioinformatics | 14:372 (10 pp)

W. Zhang, D. Feng, R. Li, A. Chernikov, N. Chrisochoides, C. Osgood, C. Konikoff, S. Newfeld, S. Kumar, S. Ji

2012
122

Exploring Spatial Patterns of Gene Expression from Fruit Fly Embryogenesis on the iPhone

Bioinformatics | 28:2847–2848

S. Kumar, K. Boccia, M. McCutchan, J. Ye

121

Sharing and Re-use of Phylogenetic Trees (and associated data) to Facilitate Synthesis

BMC Research Notes | 5:574 (15 pp)

A. Stoltzfus, B. O'Meara, J. Whitacre, R. Mounce, E. L. Gillespie, S. Kumar, D.F. Rosauer, R.A. Vos

120

Evolutionary Meta-analysis of Association Studies Reveals Ancient Constraints Affecting Disease Marker Discovery

Molecular Biology and Evolution | 29:2087–2094

J.T. Dudley, R. Chen, M.D. Sanderford, A.J. Butte, S. Kumar

119

Human Genomic Disease Variants: A Neutral Evolutionary Explanation

Genome Research | 22:1383–1394

J.T. Dudley, Y. Kim, L. Liu, G. J. Markov, K. Gerold, R. Chen, A.J. Butte, S. Kumar

118

Performance of Computational Tools in Evaluating the Functional Impact of Laboratory-induced Amino Acid Mutations

Bioinformatics | 28:2093–2096

V.E. Gray, K.R. Kukurba, S. Kumar

117

Comparison of Embryonic Expression within Multigene Families using the FlyExpress Discovery Platform Reveals More Spatial than Temporal Divergence

Developmental Dynamics | 241:150–160

C. Konikoff, T.L. Karr, M. McCutchan, S.J. Newfeld, S. Kumar

116

Statistics and Truth in Phylogenomics

Molecular Biology and Evolution | 29:457–472

S. Kumar, A.J. Filipski, F.U. Battistuzzi, S. L. K. Pond, K. Tamura

115

Evolutionary Diagnosis Method for Variants in Personal Exomes

Nature Methods | 9:855–856

S. Kumar, M.D. Sanderford, V.E. Gray, J. Ye, L. Liu

114

MEGA-CC: Computing Core of Molecular Evolutionary Genetics Analysis Program for Automated and Iterative Data Analysis

Bioinformatics | 28:2685–2686

S. Kumar, G. Stecher, D. Peterson, K. Tamura

113

Drosophila Gene Expression Pattern Annotation through Multi-instance Multi-label Learning

IEEE/ACM Transactions on Computational Biology and Bioinformatics | 9:98–112

Y.X. Li, S. Ji, S. Kumar, J. Ye, Z.H. Zhou

112

Purifying Selection Modulates the Estimates of Population Differentiation and Confounds Genome-wide Comparisons across Single-nucleotide Polymorphisms

Molecular Biology and Evolution | 29:3617–3623

T. Maruki, S. Kumar, Y. Kim

111

Estimating Divergence Times in Large Molecular Phylogenies

Proceedings of the National Academy of Sciences (USA) | 109:19333–19338

K. Tamura, F.U. Battistuzzi, P. Billing-Ross, O. Murillo, A. Filipski, S. Kumar

110

Learning Sparse Representations for Fruit-fly Gene Expression Pattern Image Annotation and Retrieval

BMC Bioinformatics | 13:107 (15 pp)

L. Yuan, A. Woodard, S. Ji, Y. Jiang, Z.H. Zhou, S. Kumar, J. Ye

2011
109

Molecular Clock: Testing

eLS | (7 pp)

F.U. Battistuzzi, A. Filipski, S. Kumar

108

Fast and Slow Implementations of Relaxed-clock Methods Show Similar Patterns of Accuracy in Estimating Divergence Times

Molecular Biology and Evolution | 28:2439–2442

F.U. Battistuzzi, P. Billing-Ross, A. Paliwal, S. Kumar

107

Stoichiogenomics: The Evolutionary Ecology of Macromolecular Elemental Composition

Trends in Ecology & Evolution | 26:38–44

J.J. Elser, C. Acquisti, S. Kumar

106

Rampant Purifying Selection Conserves Positions with Posttranslational Modifications in Human Proteins

Molecular Biology and Evolution | 28:1565–1568

V.E. Gray, S. Kumar

105

Phylomedicine: An Evolutionary Telescope to Explore and Diagnose the Universe of Disease Mutations

Trends in Genetics | 27:377–386

S. Kumar, J.T. Dudley, A. Filipski, L. Liu

103

FlyExpress: Visual Mining of Spatiotemporal Patterns for Genes and Publications in Drosophila Embryogenesis

Bioinformatics | 27:3319–3320

S. Kumar, C. Konikoff, B. Van Emden, C. Busick, K.T. Davis, S. Ji, L.W. Wu, H. Ramos, T. Brody, S. Panchanathan, J. Ye, T. L. Karr, K. Gerold, M. McCutchan, S. J. Newfeld

102

Evolution of Modern Birds Revealed by Mitogenomics: Timing the Radiation and Origin of Major Orders

Molecular Biology and Evolution | 28:1927–1942

M.A. Pacheco, F.U. Battistuzzi, M. Lentino, R.F. Aguilar, S. Kumar, A. Escalante

101

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

Molecular Biology and Evolution | 28:2731–2739

K. Tamura, D. Peterson, N. Peterson, G. Stecher, M. Nei, S. Kumar

2010
100

Performance of Relaxed-clock Methods in Estimating Evolutionary Divergence Times and Their Credibility Intervals

Molecular Biology and Evolution | 27:1289–1300

F.U. Battistuzzi, A. Filipski, S.B. Hedges, S. Kumar

Quantitative Analysis of the Drosophila Segmentation Regulatory Network Using Pattern Generating Potentials

PLoS Biology | 8:(19 pp)

M. Kazemian, C. Blatti, A. Richards, M. McCutchan, N. Wakabayashi-Ito, A.S. Hammonds, S.E. Celniker, S. Kumar, S.A. Wolfe, M.H. Brodsky, S. Sinha

More Reliable Estimates of Divergence Times in Pan Using Complete mtDNA Sequences and Accounting for Population Structure

Philosophical Transactions of the Royal Society B: Biological Sciences | 365:3277–3288

A.C. Stone, F.U. Battistuzzi, L.S. Kubatko, G.H. Perry, Jr., E. Trudeau, H. Lin, S. Kumar

2009

Ecological Nitrogen Limitation Shapes the DNA Composition of Plant Genomes

Molecular Biology and Evolution | 26:953–956

C. Acquisti, J.J. Elser, S. Kumar

96

The Timetree of Life

Oxford University Press (New York) | (551 pp)

S.B. Hedges, S. Kumar

95

Discovering the Timetree of Life

The TimeTree of Life (ed. Hedges, Kumar) [Oxford University Press] | 3–18

S.B. Hedges, S. Kumar

Signatures of Nitrogen Limitation in the Elemental Composition of the Proteins Involved in the Metabolic Apparatus

Proceedings of the Royal Society B: Biological Sciences | 276:2605–2610

C. Acquisti, S. Kumar, J.J. Elser

Association of Orthodenticle with Natural Variation for Early Embryonic Patterning in Drosophila melanogaster

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution | 312:841–854

L.M. Goering, P.K. Hunt, C. Heighington, C. Busick, P.S. Pennings, J. Hermisson, S. Kumar, G. Gibson

Phylogenetic Construction of 17 Bacterial Phyla by New Method and Carefully Selected Orthologs

Gene | 429:59–64

T. Horiike, D. Miyata, K. Hamada, S. Saruhashi, T. Shinozawa, S. Kumar, R. Chakraborty, T. Komiyama, Y. Tateno

A Bag-of-words Approach for Drosophila Gene Expression Pattern Annotation

BMC Bioinformatics | 10:119 (16 pp)

S. Ji, Y.X. Li, Z.H. Zhou, S. Kumar, J. Ye

Drosophila Gene Expression Pattern Annotation Using Sparse Features and Term-term Interactions

KDD-09: 15th ACM SIGKDD Conference on Knowledge Discovery and Data Mining | 407–415

S. Ji, L. Yuan, Y.X. Li, Z.H. Zhou, S. Kumar, J. Ye

Positional Conservation and Amino Acids Shape the Correct Diagnosis and Population Frequencies of Benign and Damaging Personal Amino Acid Mutations

Genome Research | 19:1562–1569

S. Kumar, M.P. Suleski, G.J. Markov, S. Lawrence, A. Marco, A.J. Filipski

Relationship between Gene Co-expression and Sharing of Transcription Factor Binding Sites in Drosophila Melanogasterc

Bioinformatics | 25:2473–2477

A. Marco, C. Konikoff, T.L. Karr, S. Kumar

The Origin of Metazoa: A Transition from Temporal to Spatial Cell Differentiation

BioEssays | 31:758–768

K.V. Mikhailov, A.V. Konstantinova, M.A. Nikitin, P.V. Troshin, L.Y. Rusin, V.A. Lyubetsky, Y.V. Panchin, A.P. Mylnikov, L.L. Moroz, S. Kumar, V.V. Aleoshin

Methods for Incorporating the Hypermutability of CpG Dinucleotides in Detecting Natural Selection Operating at the Amino Acid Sequence Level

Molecular Biology and Evolution | 26:2275–2284

Y. Suzuki, T. Gojobori, S. Kumar

2008

Developmental Stage Annotation of Drosophila Gene Expression Pattern Images via an Entire Solution Path for LDA

ACM Transactions on Knowledge Discovery from Data | 2:(21 pp)

J. Ye, J. Chen, R. Janardan, S. Kumar

84

Biological Image Analysis via Matrix Approximation

Encyclopedia of Data Warehousing and Mining (ed. Wang) [Idea Group] | 166–170

J. Ye, R. Janadan, S. Kumar

Automated Annotation of Drosophila Gene Expression Patterns Using a Controlled Vocabulary

Bioinformatics | 24:1881–1888

S. Ji, L. Sun, R. Jin, S. Kumar, J. Ye

MEGA: A Biologist-centric Software for Evolutionary Analysis of DNA and Protein Sequences

Briefings in Bioinformatics | 9:299–306

S. Kumar, M. Nei, J. Dudley, K. Tamura

2007
81

Detecting Molecular Signatures of Adaptive Evolution

Evolutionary Genomics and Proteomics (ed. Pagel, Pomiankowski) [Sinauer] | 241–254

A. Filipski, S. Prohaska, S. Kumar

Nullomers: Really a Matter of Natural Selection?

PLoS One | 2:1022–1025

C. Acquisti, G. Poste, D. Curtiss, S. Kumar

Evolution of Genes and Genomes on the Drosophila Phylogeny

Nature | 450:203–218

A.G. Clark, M.B. Eisen, D.R. Smith, C.M. Bergman, B. Oliver, T.A. Markow, T.C. Kaufman, M. Kellis, W. Gelbart, V.N. Iyer, D.A. Pollard, T.B. Sackton, S. Kumar, et al

Lower Bounds on Multiple Sequence Alignment Using Exact 3-way Alignment

BMC Bioinformatics | 8:140 (8 pp)

C.J. Colbourn, S. Kumar

Bioinformatics Software for Biologists in the Genomics Era

Bioinformatics | 23:1713–1717

S. Kumar, J. Dudley

Multiple Sequence Alignment: In Pursuit of Homologous DNA Positions

Genome Research | 17:127–135

S. Kumar, A. Filipski

MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0

Molecular Biology and Evolution | 24:1596–1599

K. Tamura, J. Dudley, M. Nei, S. Kumar

Constraint and Turnover in Sex-biased Gene Expression in the Genus Drosophila

Nature | 450:233–237

Y. Zhang, D. Sturgill, M. Parisi, S. Kumar, B. Oliver

2006

Classification of Drosophila Embryonic Developmental State Range Based on Gene Expression Pattern Images

Computational Systems Bioinformatics Conference | 2006:293–298

J. Ye, J. Chen, Q. Li, S. Kumar

Codon-based Detection of Positive Selection Can be Biased by Heterogeneous Distribution of Polar Amino Acids along Protein Sequences

Computational Systems Bioinformatics Conference | 2006:335–340

X. Xia, S. Kumar

Signatures of Ecological Resource Availability in the Animal and Plant Proteomes

Molecular Biology and Evolution | 23:1946–1951

J.J. Elser, W.F. Fagan, S. Subramanian, S. Kumar

TimeTree: A Public Knowledge-base of Divergence Times among Organisms

Bioinformatics | 22:2971–2972

S.B. Hedges, J. Dudley, S. Kumar

Constraining Fossil Calibrations for Molecular Clocks

BioEssays | 28:770–771

S.B. Hedges, S. Kumar, M. Van Tuinen

Evolutionary Anatomies of Positions and Types of Disease-associated and Neutral Amino Acid Mutations in the Human Genome

BMC Genomics | 7:306 (9 pp)

S. Subramanian, S. Kumar

Higher Intensity of Purifying Selection on >90% of the Human Genes Revealed by the Intrinsic Replacement Mutation Rates

Molecular Biology and Evolution | 23:2283–2287

S. Subramanian, S. Kumar

2005
66

The Evolution of the Genome: Comparative Genomics in Eukaryotes

The Evolution of the Genome (ed. Gregory) [Elsevier] | 521–583

A. Filipski, S. Kumar

Maximum Likelihood Outperforms Maximum Parsimony Even When Evolutionary Rates are Heterotachous

Molecular Biology and Evolution | 22:2139–2141

S. Gadagkar, S. Kumar

Inferring Species Phylogenies from Multiple Genes: Concatenated Sequence Tree versus Consensus Gene Tree

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution | 304:64–74

S. Gadagkar, M. Rosenberg, S. Kumar

Automatic Annotation Techniques for Gene Expression Images of the Fruit Fly Embryo

Visual Communications and Image Processing 2005, Pts 1-4 | 5960:576–583

M. Gargesha, J. Yang, B. Van Emden, S. Panchanathan, S. Kumar

Molecular Clocks: Four Decades of Evolution

Nature Reviews Genetics | 6:654–662

S. Kumar

Placing Confidence Limits on the Molecular Age of the Human-Chimpanzee Divergence

Proceedings of the National Academy of Sciences (USA) | 102:18842–18847

S. Kumar, A. Filipski, V. Swarna, A. Walker, S.B. Hedges

Pushing Back the Expansion of Introns in Animal Genomes

Cell | 123:1182–1184

S. Kumar, S.B. Hedges

2004
59

Image Registration and Similarity Computation for Chicken Gene Expression Patterns

Genomic Signal Processing and Statistics | (4 pp)

M. Gargesha, P. Antin, B. Van Emden, S. Panchanathan, S. Kumar

The Spectrum of Human Rhodopsin Disease Mutations through the Lens of Interspecific Variation

Gene | 12:107–118

A. Briscoe, C. Gaur, S. Kumar

Identifying Spatially Similar Gene Expression Patterns in Early Stage Fruit Fly Embryo Images: Binary Feature versus Invariant Moment Digital Representations

BMC Bioinformatics | 16:202–214

R. Gurunathan, B. Van Emden, S. Panchanathan, S. Kumar

Precision of Molecular Time Estimates

Trends in Genetics | 20:242–247

S.B. Hedges, S. Kumar

Gene Expression Intensity Shapes Evolutionary Rates of the Proteins Encoded by the Vertebrate Genome

Genetics | 168:373–381

S. Subramanian, S. Kumar

Prospects for Inferring Very Large Phylogenies by Using the Neighbor-joining Method

Proceedings of the National Academy of Sciences (USA) | 101:11030–11035

K. Tamura, M. Nei, S. Kumar

Temporal Patterns of Fruit Fly (Drosophila) Evolution Revealed by Mutation Clocks

Molecular Biology and Evolution | 21:36–44

K. Tamura, S. Subramanian, S. Kumar

MEGA3: Integrated Software for Molecular Evolutionary Genetics Analysis and Sequence Alignment

Briefings in Bioinformatics | 5:150–163

S. Kumar, K. Tamura, M. Nei

2003

Genomic Clocks and Evolutionary Timescales

Trends in Genetics | 19:200–206

S.B. Hedges, S. Kumar

Genomic Sequence of a Ranavirus (family Iridoviridae) Associated with Salamander Mortalities in North America

Virology | 316:90–103

J. Jancovich, J. Mao, V. Chinchar, C. Wyatt, S. Case, S. Kumar, G. Valente, S. Subramanian, E. Davidson, J. Collins, B. Jacobs

Quantifying the Intragenic Distribution of Human Disease Mutations

Annals of Human Genetics | 67:567–579

M. Miller, J. Parker, S. Rissing, S. Kumar

Heterogeneity of Nucleotide Frequencies among Evolutionary Lineages and Phylogenetic Inference

Molecular Biology and Evolution | 20:610–621

M. Rosenberg, S. Kumar

Taxon Sampling, Bioinformatics, and Phylogenomics

Systematic Biology | 52:119–124

M. Rosenberg, S. Kumar

Patterns of Transitional Mutation Biases within and among Mammalian Genomes

Molecular Biology and Evolution | 20:988–993

M. Rosenberg, S. Subramanian, S. Kumar

Neutral Substitutions Occur at a Faster Rate in Exons than in Noncoding DNA in Primate Genomes

Genome Research | 13:838–844

S. Subramanian, S. Kumar

2002

Vertebrate Genomes Compared

Science | 297:1283–1285

S.B. Hedges, S. Kumar

Measuring Conservation of Contiguous Sets of Autosomal Markers on Bovine and Porcine Genomes in relation to the Map of the Human Genome

Genome | 45:769–776

Z. Jiang, J. Melville, H. Cao, S. Kumar, A. Filipski, A. Gibbins

BEST: A Novel Computational Approach for Comparing Gene Expression Patterns from Early Stages of Drosophila melanogaster Development

Genetics | 162:2037–2047

S. Kumar, K. Jayaraman, S. Panchanathan, R. Gurunathan, A. Marti-Subirana, S. Newfeld

Mutation Rates in Mammalian Genomes

Proceedings of the National Academy of Sciences (USA) | 99:803–808

S. Kumar, S. Subramanian

Evolutionary Distance Estimation under Heterogeneous Substitution Pattern among Lineages

Molecular Biology and Evolution | 19:1727–1736

K. Tamura, S. Kumar

2001
39

Elucidating Gene Interaction Networks Based on Gene Expression Pattern Image Analysis

Proceedings of the International Conference on Biomedical Engineering | 5:232–234

S. Kumar, S. Panchanathan

Does Nonneutral Evolution Shape Observed Patterns of DNA Variation in Animal Mitochondrial Genomes?

Annual Review of Genetics | 35:539–566

A. Gerber, R. Loggins, S. Kumar, T. Dowling

A Genomic Timescale for the Origin of Eukaryotes

BMC Evolutionary Biology | 1:4 (10 pp)

S.B. Hedges, H. Chen, S. Kumar, D.Y.C. Wang, A.S. Thompson, H. Watanabe

Mutation and Linkage Disequilibrium in Human mtDNA

European Journal of Human Genetics | 9:969–972

P. Hedrick, S. Kumar

Classification and Indexing of Gene Expression Images

Applications of Digital Image Processing XXIV | 4472:471–481

K. Jayaraman, S. Panchanathan, S. Kumar, A. Tescher

Disparity Index: A Simple Statistic to Measure and Test the Homogeneity of Substitution Patterns between Molecular Sequences

Genetics | 158:1321–1327

S. Kumar, S. Gadagkar

Determination of the Number of Conserved Chromosomal Segments between Species

Genetics | 157:1387–1395

S. Kumar, S. Gadagkar, A. Filipski, X. Gu

MEGA2: Molecular Evolutionary Genetics Analysis Software

Bioinformatics | 17:1244–1245

S. Kumar, K. Tamura, I. Jakobsen, M. Nei

Understanding Human Disease Mutations through the Use of Interspecific Genetic Variation

Human Molecular Genetics | 10:2319–2328

M. Miller, S. Kumar

Incomplete Taxon Sampling is Not a Problem for Phylogenetic Inference

Proceedings of the National Academy of Sciences (USA) | 98:10751–10756

M. Rosenberg, S. Kumar

Traditional Phylogenetic Reconstruction Methods Reconstruct Shallow and Deep Evolutionary Relationships Equally Well

Molecular Biology and Evolution | 18:1823–1827

M. Rosenberg, S. Kumar

2000

Efficiency of the Neighbor-joining Method in Reconstructing Deep and Shallow Evolutionary Relationships in Large Phylogenies

Journal of Molecular Evolution | 51:544–553

S. Kumar, S. Gadagkar

Questioning Evidence for Recombination in Human Mitochondrial DNA

Science | 288:1931a (2 pp)

S. Kumar, P. Hedrick, T. Dowling, M. Stoneking

Expansion and Molecular Evolution of the Interferon-induced 2 '-5 ' Oligoadenylate Synthetase Gene Family

Molecular Biology and Evolution | 17:738–750

S. Kumar, C. Mitnik, G. Valente, G. Floyd-Smith

25

Molecular Evolution and Phylogenetics

Oxford University Press [New York] | (333 pp)

M. Nei, S. Kumar

Single Column Discrepancy and Dynamic Max-Mini Optimizations for Quickly Finding the Most Parsimonious Evolutionary Trees

Bioinformatics | 16:140–151

P. Purdom, P. Bradford, K. Tamura, S. Kumar

1999

Molecular Evolution of a Developmental Pathway: Phylogenetic Analyses of Transforming Growth Factor-beta Family Ligands, Receptors and Smad Signal Transducers

Genetics | 152:783–795

S. Newfeld, R. Wisotzkey, S. Kumar

Divergence Time Estimates for the Early History of Animal Phyla and the Origin of Plants, Animals and Fungi

Proceedings of the Royal Society B: Biological Sciences | 266:163–171

D. Wang, S. Kumar, S.B. Hedges

Divergence Times of Eutherian Mammals

Science | 285:2031a (2 pp)

S.B. Hedges, S. Kumar

20

Genome Maps 10. Comparative Genomics. Mammalian Radiations. Wall Chart.

Science | 286:463–478

S.J. O'Brien, J.F. Eisenberg, M. Miyamoto, S.B. Hedges, S. Kumar, D.E. Wilson, M. Menotti-Raymond, W.J. Murphy, W.G. Nash, L.A. Lyons, J.C. Menninger, R. Stanyon, J. Wienberg, N.G. Copeland, N.A. Jenkins, J. Gellin, M. Yerle, L. Andersson, J. Womack, T. Broad, J. Postlethwait, et al.

1998

A Molecular Timescale for Vertebrate Evolution

Nature | 392:917–920

S. Kumar, S.B. Hedges

The Optimization Principle in Phylogenetic Analysis Tends to Give Incorrect Topologies When the Number of Nucleotides or Amino Acids Used is Small

Proceedings of the National Academy of Sciences (USA) | 95:12390–12397

M. Nei, S. Kumar, K. Takahashi

1997

Evolution and Functional Diversification of the Paired Box (Pax) DNA-binding Domains

Molecular Biology and Evolution | 14:829–842

K. Balczarek, Z. Lai, S. Kumar

Detection of Convergent and Parallel Evolution at the Amino Acid Sequence Level

Molecular Biology and Evolution | 14:527–536

J. Zhang, S. Kumar

Sequence Convergence in the Peptide-binding Region of Primate and Rodent MBC Class Ib Molecules

Molecular Biology and Evolution | 14:1035–1041

M. Yeager, S. Kumar, A. Hughes

Tempo and Mode of Nucleotide Substitutions in GAG and ENV Gene Fragments in Human Immunodeficiency Virus Type 1 Populations with a Known Transmission History

Journal of Virology | 71:4761–4770

T. Leitner, S. Kumar, J. Albert

Small-sample Tests of Episodic Adaptive Evolution: A Case Study of Primate Lysozymes

Molecular Biology and Evolution | 14:1335–1338

J. Zhang, S. Kumar, M. Nei

1996

Stepwise Algorithm for Finding Minimum Evolution Trees

Molecular Biology and Evolution | 13:584–593

S. Kumar

Patterns of Nucleotide Substitution in Mitochondrial Protein Coding Genes of Vertebrates

Genetics | 143:537–548

S. Kumar

Evolutionary Relationships of Eukaryotic Kingdoms

Journal of Molecular Evolution | 42:183–193

S. Kumar, A. Rzhetsky

Evolution of the Hedgehog Gene Family

Genetics | 142:965–972

S. Kumar, K. Balczarek, Z. Lai

Approximate Methods for Estimating the Pattern of Nucleotide Substitution and the Variation of Substitution Rates among Sites

Molecular Biology and Evolution | 13:650–659

Z. Yang, S. Kumar

Continental Breakup and the Ordinal Diversification of Birds and Mammals

Nature | 381:226–229

S.B. Hedges, P. Parker, C. Sibley, S. Kumar

1995

A New Method of Inference of Ancestral Nucleotide and Amino Acid Sequences

Genetics | 141:1641–1650

Z. Yang, S. Kumar, M. Nei

Four-cluster Analysis: A Simple Method to Test Phylogenetic Hypotheses

Molecular Biology and Evolution | 12:163–167

A. Rzhetsky, S. Kumar, M. Nei

18S Ribosomal-RNA Data Indicate that Aschelminthes are Polyphyletic in Origin and Consist of at Least Three Distinct Clades

Molecular Biology and Evolution | 12:1132–1137

B. Winnepenninckx, T. Backeljau, L. Mackey, J. Brooks, R. De Watcher, S. Kumar, J. Garey

1994

MEGA - Molecular Evolutionary Genetics Analysis Software for Microcomputers

Computer Applications in the Biosciences | 10:189–191

S. Kumar, K. Tamura, M. Nei

1993
2

A Guide to Molecular Evolutionary Genetics Analysis Program for Microcomputers

Pennsylvania State University [University Park, PA, USA] | (135 pp)

S. Kumar, K. Tamura, M. Nei

1992

Human Origins and Analysis of Mitochondrial DNA Sequences

Science | 255:737–739

S.B. Hedges, S. Kumar, K. Tamura, M. Stoneking